Background: The expansion of the use of audio and video media technology has faced society with many medical, cultural and economic challenges. In the meantime, excessive use of mobile phones can cause many problems. Objective: The aim of this study was to construct and validate a questionnaire on physical and psychological injuries of mobile phones. Method: The Method of the present study was descriptive-correlational and confirmatory factor analysis. The statistical population of the study consisted of all citizens of Khorramabad with a diploma or higher in 1399, which was selected as a statistical sample by available sampling Method of 200 people online and virtual. Results: The results showed that the factorized physical and psychological harm questionnaire of cell phone with 42 questions and 10 components (fear of loss, vibration syndrome, duck syndrome, nomophobia, insomnia, hearing problem, eye syndrome, tunnel and neck syndrome SMS) and has good reliability, validity and flexibility in terms of psychometrics. Discussion and Conclusion: The questionnaire of factor analysis of physical and psychological injuries of mobile phones can be used to identify and study the physical and psychological injuries of mobile phones.

High-performance liquid chromatography (HPLC) is recognized as a primary separation technique in modern pharmaceutical and biomedical analyses due to its exceptional efficiency and high sensitivity in detecting the analyte of interest. In the analysis of pharmaceutical samples, it is essential to ensure the reliability of the produced results. Method validation is a critical stage in the development of analytical Methods, determining whether these Methods are suitable and reliable for their intended purposes. The databases including PubMed, PubMed Central, Google Scholar, and ICHQ2R2 were searched using keywords such as HPLC, validation, Accuracy, and Precision. To meet the requirements set by Good Manufacturing Practice (GMP) guidelines, pharmaceutical companies must establish a program to monitor and evaluate all their processes. The primary goal of this effort is to standardize all processes involved in the industry, including development, manufacturing, production, and analytical Methods. This review article aims to provide insightful guidance on conducting validation for analytical Methods that employed in pharmaceutical analysis. Specifically, it focuses on the validation process as per ICH Guidelines, which encompasses a comprehensive evaluation of performance characteristics such as accuracy, precision, specificity, linearity, working range, limit of detection, limit of quantification, robustness.

Analytical Methods play significant role in many branches such as, food production, natural product analysis, environmental analysis, pharmaceutical and biomedical analysis, and life sciences, etc. In order to reach reliable, accurate and repeatable data validated analytical Methods need to achieve this aim.....